翻訳と辞書 Words near each other ・ Interferometric modulator display ・ Interferometric reflectance imaging ・ Interferometric scattering microscopy ・ Interferometric synthetic aperture radar ・ Interferometric visibility ・ Interferometry ・ Interferomics ・ Interferon ・ Interferon alfa ・ Interferon alfa 2b ・ Interferon alfacon-1 ・ Interferon alpha 1 ・ Interferon alpha-n3 ・ Interferon beta 1a ・ Interferon beta 1b ・ Interferon gamma ・ Interferon gamma 5' UTR regulatory element ・ Interferon gamma receptor (IFNGR1) family ・ Interferon gamma receptor 1 ・ Interferon gamma receptor 2 ・ Interferon gamma release assay ・ Interferon induced transmembrane protein 5 ・ Interferon regulatory factors ・ Interferon tau ・ Interferon type I ・ Interferon type II ・ Interferon type III ・ Interferon-alpha/beta receptor ・ Interferon-gamma receptor ・ Interferon-inducible GTPase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Interferon gamma ： ウィキペディア英語版 Interferon gamma Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a product of antigen-stimulated lymphocytes〔Wheelock, EF, Interferon-like virus inhibitor induced in human leukocytes by phytohemagglutinin. ''Science'' 149, 310-311, 1965. It was also shown to be produced in human lymphocytes 〕 or tuberculin-sensitized mouse peritoneal lymphocytes challenged with PPD; the resulting supernatants were shown to inhibit growth of vesicular stomatitis virus. Those reports also contained the basic observation underlying the now widely employed interferon gamma release assay used to test for tuberculosis. In humans, the IFNγ protein is encoded by the ''IFNG'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3460 )〕 ==Function== IFNγ, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFNγ is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. Aberrant IFNγ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNγ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3458 )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Interferon gamma」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.